Breast cancer treatment breakthrough
The groundbreaking study has uncovered new reasons as to why breast cancer arises
The new research suggests that
cancers are highly individual, which could lead to new treatments ARMEND
NIMANI/AFP/Getty Images
The latest breast cancer research could lead
to more personalised care for patients and help further understanding of the
causes of the disease, scientists said.
A study involving people from around the world
has been hailed as giving a more complete picture of the changes in DNA in
breast cancer, providing potential opportunities for new treatments.
A study of 560 breast cancer genomes, or
complete genetic codes, turned up five new genes associated with the disease.
The results, published in Nature and Nature
Communications, provide evidence that breast cancer genomes are "highly
individual", researchers from the Wellcome Trust Sanger Institute said.
The team looked at genomes in patients, four
of whom were men, and focused on mutations that encourage the disease to grow
and the patterns - known as mutational signatures - in each tumour.
They found that women with genes that leave
them at a higher risk of developing breast and ovarian cancer, have entire
genome profiles that are very different to each other and distinctive from
other breast cancers.
Dr Serena Nik-Zainal, who led the team of
researchers, said: "In the future, we'd like to be able to profile
individual cancer genomes so that we can identify the treatment most likely to
be successful for a woman or man diagnosed with breast cancer. It is a step
closer to personalised healthcare for cancer."
AP
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